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Chinese Journal of Natural Medicines (English Ed.) ; (6): 950-954, 2017.
Article in English | WPRIM | ID: wpr-812036

ABSTRACT

In the present study, one new cycloartane triterpenoid, named cycloccidentalic acid C (1) and its glucoside, cycloccidentaliside VI (2) were isolated from the whole plant of Cassia occidentalis. Their structures were elucidated by a combinational analyses of 1D and 2D NMR data and HRMS. Compound 2 showed modest anti-HIV-1 activity with EC value of 1.44 μmol·L and TI (Therapeutic Index) value of 15.59.


Subject(s)
Humans , Anti-HIV Agents , Pharmacology , Cell Line, Tumor , Cell Survival , Glucosides , Chemistry , Pharmacology , Toxicity , Inhibitory Concentration 50 , Magnetic Resonance Spectroscopy , Molecular Structure , Plant Extracts , Chemistry , Pharmacology , Toxicity , Senna Plant , Chemistry , Triterpenes , Chemistry , Pharmacology , Toxicity
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